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CRISPER, TALENS and RNAi, frequently in news, are technologies associated with
Genome Manipulation
Space Exploration
Disaster Management
Nano-technology
CRISPR (other two not needed to be explained here) is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat. This name refers to the unique organization of short, partially palindromic repeated DNA sequences found in the genomes of bacteria and other microorganisms. While seemingly innocuous, CRISPR sequences are a crucial component of the immune systems of these simple life forms. The immune system is responsible for protecting an organism’s health and well-being. Just like us, bacterial cells can be invaded by viruses, which are small, infectious agents.
If a viral infection threatens a bacterial cell, the CRISPR immune system can thwart the attack by destroying the genome of the invading virus. The genome of the virus includes genetic material that is necessary for the virus to continue replicating. Thus, by destroying the viral genome, the CRISPR immune system protects bacteria from ongoing viral infection. A DBT Task Force’s purpose is to help establish accessible facilities on some emerging technologies. Genome Manipulation, Editing and Interference by CRISPER, TALENS and RNAi Nucleic Acid Chips for genetic variations and chromatin remodelling Single Cell Genomics and Mass-Cytometry
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