Explanation:

- Fatigue: This word means extreme tiredness or exhaustion. It usually refers to a physical or mental state where one feels very weary and lacks energy.

- Option 1: Liveliness: This means energy and enthusiasm. It is the opposite of fatigue because it implies being full of energy.

- Option 2: Weariness: This means tiredness or a feeling of being worn out. It is a direct synonym of fatigue, as both refer to a state of exhaustion or tiredness.

- Option 3: Earnestness: This refers to being serious and sincere. It is not related to feeling tired or exhausted.

- Option 4: Freshness: This means being full of life and energy or the state of being new or clean. Like liveliness, it is almost the opposite of fatigue.