Explanation:

- Axiom-4: Axiom missions are part of private endeavors to the ISS. They often carry out microgravity research, supporting scientific experiments in the unique low-gravity environment.

- SpaDeX: This mission likely refers to a research initiative or experiment designed for space, including microgravity studies. Such experiments aid in understanding the impacts of space conditions on various phenomena.

- Gaganyaan: India's crewed space mission aims to develop indigenous capabilities for human spaceflight. While its primary focus is launching humans into space, it also includes objectives related to microgravity research.

- Option 1: Incorrect as more than one mission supports microgravity research.

- Option 2: Incorrect as all three missions support or have the potential to support microgravity research.

- Option 3: Correct as all the three missions involve or encourage microgravity research.

- Option 4: Incorrect as at least one mission clearly involves microgravity research.

The correct answer is: Option 3: All the three