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Consider the following statements regarding ‘Hydrogel developed for Targeted Breast Cancer Therapy’
Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids.
They serve as a stable reservoir for anti-cancer drugs, releasing it in a controlled manner while sparing healthy cells from harm.
The hydrogel remained localised at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs.
Which of the statements given above is/are correct?
1&2 only
2 only
2&3 only
1,2&3
Researchers from the Indian Institute of Technology-Guwahati (IIT-G) and the Bose Institute, Kolkata have developed an advanced injectable hydrogel for localised cancer treatment.
Statement 1 is correct: Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids. Their unique structure mimics living tissues, making them suitable for biomedical applications.
The hydrogel, composed of ultra-short peptides — biocompatible and biodegradable building blocks of proteins — is designed to remain insoluble in biological fluids, ensuring it stays localised at the injection site.
It responds to elevated glutathione (GSH) levels, a molecule abundant in tumour cells.
Upon encountering high GSH levels, the hydrogel triggers a controlled drug release directly into the tumour, minimising its interaction with healthy tissues and reducing systemic side effects.
Statement 2 is correct: They serve as a stable reservoir for anti-cancer drugs, releasing it in a controlled manner while sparing healthy cells from harm.
Statement 3 is correct: The hydrogel remained localised at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs.
Hence option 4th is correct.
By: Shubham Tiwari ProfileResourcesReport error
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