Explanation:

- Let's look at each option:

- Option 1: 28 = 2 × 2 × 7 (not a cube, not a product of 2 primes)

- Option 2: 217 = 7 × 31 (product of two primes)

- Option 3: 338 = 2 × 13 × 13 (not a cube, not a product of 2 primes)

- Option 4: 65 = 5 × 13 (product of two primes)

- Three numbers (28, 217, 65) are products of two prime numbers or just simple products, while 338 is the only number which is neither a product of just two primes nor follows cube or square logic.

- 338 stands out as it is not the product of two distinct primes, or a cube.

Option 3: 338 is the different one.