Explanation:

- Prashant Kishor: He is a well-known Indian political strategist and tactician. His work has significantly impacted Indian politics, influencing several major election outcomes. However, he is based in India, not the U.S.

- Hasan Minhaj:  Correct Answer He is a U.S.-based Indian-American comedian and political commentator. Known for his work on "The Daily Show" and his Netflix show "Patriot Act with Hasan Minhaj," he has garnered attention for his insightful and humorous take on social and political issues.

- Mahua Moitra: An Indian politician and member of the All India Trinamool Congress, known for her eloquent speeches in the Indian Parliament. She is not U.S.-based.

- Dushyant Chautala: He is an Indian politician, serving as the Deputy Chief Minister of Haryana. Like Moitra, he is India-based and involved in regional politics.

In summary, Hasan Minhaj, with his engaging mix of humor and social commentary, is the one to watch in the 2020s from the U.S. Indian diaspora.