Explanation:

- Option 1: Karle

- Karle is a famous site known for its Buddhist rock-cut caves.

- It is located in Maharashtra, not Uttar Pradesh.

- Option 2: Sarnath

- Sarnath is one of the most revered Buddhist sites.

- It is indeed located in Uttar Pradesh.

- This is where Lord Buddha delivered his first sermon.

- Option 3: Amaravati

- Amaravati is known for its ancient Buddhist stupas.

- It is located in Andhra Pradesh, not Uttar Pradesh.

- Option 4: Sanchi

- Sanchi is famous for its stunning stupa and Buddhist monuments.

- It is located in Madhya Pradesh.