Multiple Choice Questions on Consider the following statements regarding CRISPR Cas9 The CRISPR component in the CRISPR Cas9 syst........... for CAPF (AC) Exam Preparation

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Study Notes

    Consider the following statements regarding CRISPR-Cas9

    1. The CRISPR component in the CRISPR-Cas9 system acts as a nuclease that cuts DNA.

    2. The Cas9 protein in the CRISPR-Cas9 system is designed to bind to specific DNA bases through complementary base-pairing.

    Select the correct statement.

    1 only

    Incorrect Answer

    2 only

    Incorrect Answer

    Both

    Incorrect Answer

    None

    Correct Answer
    Explanation:
    • Scientists from the CSIR-Institute of Genomics and Integrative Biology, New Delhi, have developed an enhanced genome-editing system that can modify DNA more precisely and more efficiently than existing CRISPR-based technologies.

    Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR-Cas9)

    • It is a Gene Editing tool and is a precise way of altering DNA. It cuts out specific strands of DNA, and replaces them with new strands.

    • CRISPR: It is the DNA-targeting part of the system which consists of an RNA molecule, or ‘guide’, designed to bind to specific DNA bases through complementary base-pairing.

    • Cas9: It stands for CRISPR-associated protein 9, & is the nuclease part that cuts the DNA.

    • The CRISPR-Cas9 system: The technology was adapted from a naturally occurring genome editing system used by bacteria as an immune defense. 

    • It helps the organisms recognise and fight off similar viruses in the future by acting  like an immune system. 

     Hence option 4th is correct.


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