Explanation:

- The word "Hope" typically means a feeling of expectation and desire for a certain thing to happen.

- Option 1: Chance – This word means the occurrence of events in the absence of any obvious intention or cause. It doesn't relate clearly as an antonym for hope.

- Option 2: Courage – This refers to the ability to do something that frightens one. It does not directly oppose hope.

- Option 3: Doubt – This refers to a feeling of uncertainty or lack of conviction, which is directly opposite to hope.

- Option 4: Optimism – This means hopefulness and confidence about the future. It's more of a synonym rather than an antonym of hope.