Explanation:

1 to 300 = 300 numbers
squares btwn 1 to 300 = 1,4,9,16,25,36,49.....289 i.e, total 17
cubes = 1,8,27,64,125,216 i.e, 5
now 1 and 64 are common so total numbers that should be removed ( 17+5-2= 20 )
total 20 term removed so 300th term would be 320

Hence, option 2 is the correct answer.