Explanation:

- Twaddle: This word means nonsense or foolish talk. It's casual, trivial, and often used to describe trivial or nonsensical speech.

- Option 1, Desolate: This describes a place that is empty, barren, or lacking people. It doesn't relate to speech or talk.

- Option 2, Renovate: To renovate means to restore something to a good state or make something new again. This is unrelated to the meaning of twaddle.

- Option 3, Facile: Facile means something that is too simple or superficial. It's more about simplicity rather than the quality of speech.

- Option 4, Foolish Talk: Specifically matches the meaning of twaddle. It's directly synonymous with nonsensical speech.

Therefore, the correct answer is:

Option 4: Foolish Talk