Explanation:

Sure! Let's analyze each part of the sentence:

- Q: Man through his tools

This introduces the subject, 'Man,' and implies action through 'tools.'

- S: has caused depletion of

This connects directly to 'Q,' indicating a resulting action, but needs an object to complete the idea.

- P: biodiversity, and change in climactic pattern thus

This specifies what has been depleted due to the actions mentioned in 'S.'

- R: leading to environmental degradation

This wraps up the consequence of the depletion mentioned in 'P.'

Let's evaluate the options:

- Option 1: QSPR

Correct sequence. It forms a coherent sentence: "Man through his tools has caused depletion of biodiversity, and change in climactic pattern thus leading to environmental degradation."

- Option 2: PQRS

Does not make sense. 'P' cannot start the sentence as there's no subject or initial action.

- Option 3: SPRQ

Incongruent flow. 'S' without 'Q' preceding it leaves the initial subject/action undefined.

- Option 4: QSRP

Incorrect order. 'R' should come after 'P' to make logical sense.

The correct answer is Option 1: QSPR.