Explanation:

- The sentence describes an artist’s design that includes elements from various cultural influences. This suggests a coming together or combination of different aspects.

- Option 1: Trained - This does not fit the context of design as it refers to being taught or skilled in a particular discipline.

- Option 2: Integrative - This word means combining parts from different sources into a whole, making it most suitable for describing a design that blends multiple cultural elements.

- Option 3: Irrational - It implies lacking logic or reason which doesn’t fit the context of design blending cultural elements.

- Option 4: Paralegal - This term refers to someone who assists lawyers and is not relevant to the design context.

- Option 5: Grandee - This denotes a nobleman or person of high rank, unrelated to the art and design context.

Option 2, "Integrative," aptly describes the design, as it captures the essence of blending diverse cultural elements.