The Subject Expert Committee on Covid-19 has approved the “emergency use” of Bharat Biotech’s Covaxin vaccine for children aged between 2-18 years old.

Key Points

• Phase-2 and Phase-3 trials of the Covaxin vaccine by Hyderabad-based Bharat Biotech on children below the age of 18 years in the months of September.
• Trial data was submitted to the Drugs and Comptroller General of India (DCGI) in October 2021.
• According to AIIMS professor, latest trials suggests that safety and immunogenicity of India’s indigenous COVID-19 vaccine is almost the same in children aged 2-18 years, as it is in adults above 18-years of age.
• Trial was done by diving children into three groups. The first group was between 12 -18 years, second group was between 6- 12 years while the third age group was between 2-6 years.

Covaxin is codenamed as BBV152. It is an inactivated virus-based COVID-19 vaccine. It was developed by Bharat Biotech in association with the Indian Council of Medical Research (ICMR). Vaccine is usually considered effective if the estimate is more than 50% with a more than 30% lower limit of the 95% confidence interval. Bharat Biotech reported the Covaxin is 64 percent effective against asymptomatic cases, 78% effective against symptomatic cases, 93% effective against severe infection while 65% effective against the Delta variant of coronavirus.

By: Brijesh Kumar