Consider the following about the disease of Sickle Cell Anemia prevalent in the Indian tribals 1 It ...........

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Consider the following about the disease of Sickle Cell Anemia prevalent in the Indian tribals.

1. It is least prevalent in the Dravidians and pre-dravidian tribes.

2. It is more severe in malaria endemic regions.

3. The sickle cell gene is passed from generation to generation in a pattern of inheritance.

Select the correct answer using the codes below.

1 and 2 only

2 and 3 only

3 only

1 only

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Explanation:

Statement 1 and 2: The prevalence of Sickle Cell Anemia is higher in the tribal belt of Central, Western and Southern India; not so much in the tribes of North-East India. It is chiefly confined to dravidians and pre-dravidians tribes inhabiting malaria endemic regions.
Statement 3: There is a little worthwhile treatment for the disease as of now but with management of disease, severity and complications can be curtailed to improve the quality of life and life span.
The sickle cell gene is passed from generation to generation in a pattern of inheritance.
Government has decided to screen three crore tribal children across the country to find the incidences of Sickle Cell Anemia among them.
• The children with Sickle Cell trait or disease are counselled through their parents not to marry the other carrying trait or disease in order to control spread of the disease to next generation.
• The Ministry organised regional training workshops in collaboration with Indian Council of Medical Research (ICMR) to facilitate State/ UTs to train adequate manpower to undertake the screening exercise using a simple and cost effective screening test developed by ICMR.
• In addition, Department of Biotechnology is involved in research to find cure of the disease.