Explanation:

- Mesothelioma is associated primarily with the inhalation or ingestion of asbestos fibers.

- Correct Answer: Option 2 - Asbestos

- Asbestos is a naturally occurring mineral that was widely used in construction and other industries for its heat resistance and insulating properties.

- Lead, Cadmium, and Arsenic are toxic substances but are not primarily linked to mesothelioma.

- Lead exposure can lead to developmental and neurological issues.

- Cadmium can cause damage to the kidneys and bone health.

- Arsenic is linked to skin cancer and other conditions, mainly through contaminated water.