Explanation:

It is not necessary that you may understand this concept, nor is it possible for us to explain all technical terms that entail in the following text. Please get a basic idea of what this technique is about. FISH is a molecular cytogenetic technique that uses fluorescent probes that bind to only those parts of the chromosome with a high degree of sequence complementarity.
It was developed by biomedical researchers in the early 1980s and is used to detect and localize the presence or absence of specific DNA sequences on chromosomes.
Fluorescence microscopy can be used to find out where the fluorescent probe is bound to the chromosomes.
FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification.
FISH can also be used to detect and localize specific RNA targets (mRNA, lncRNA and miRNA) in cells, circulating tumor cells, and tissue samples. In this context, it can help define the spatial- temporal patterns of gene expression within cells and tissues