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Researchers have discovered a new class of antibiotics- Odilorhabdins. These are produced by
Secretions of budding bees in tropical forests
Botulism in packaged food items
Symbiotic bacteria found in soil-dwelling nematode worms
Grapefruit seed extract
Called odilorhabdins, or ODLs, the antibiotics are produced by symbiotic bacteria found in soil-dwelling nematode worms that colonise insects for food. The bacteria help to kill the insect, and secrete the antibiotic to keep competing bacteria away. ODLs act on the ribosome — the molecular machine that makes proteins cells needed to function — of bacterial cells. When bound to the ribosome, the antibiotic disrupts its ability to interpret and translate genetic code. When ODLs are introduced to the bacterial cells, they impact the reading ability of the ribosome and cause the ribosome to make mistakes when it creates new proteins. This miscoding corrupts the cell with flawed proteins and causes the bacterial cell to die. Odilorhabdins is unique and promising on two fronts: its unconventional source and its distinct way of killing bacteria, both of which suggest the compound may be effective at treating drug-resistant or hard- to-treat infections
By: kamaljeet kaur ProfileResourcesReport error
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