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It is a slow progressing indigenous disease caused by a protozoan parasite of genus Leishmania. Sandfly of genus Phlebotomus argentipes are the only known vectors of kala-azar in India The parasite primarily infects reticuloendothelial system and may be found in abundance in bone marrow, spleen and liver. Indian Kala-azar has a unique epidemiological feature of being Anthroponotic; human is the only known reservoir of infection Female snadflies pick up parasite (Amastigote or LD bodies)while feeding on an infected human host. Kala-azar is endemic to the Indian subcontinent in 119 districts in four countries (Bangladesh, Bhutan, India and Nepal). This disease is the second-largest parasitic killer in the world. Elimination is defined as reducing the annual incidence of Kala Azar (KA) to less than 1 case per 10,000 people at the sub-district level. Signs and symptoms include fever, weight loss, fatigue, anemia, and substantial swelling of the liver and spleen. Without proper diagnosis and treatment, is associated with high fatality. India has missed the 2017 deadline that Finance Minister Arun Jaitley had announced for elimination of Kala Azar (black fever) in his Budget speech last year. In fact, endemic blocks have increased from 61 to 68 in 17 districts of Bihar and Jharkhand.
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