Widespread resistance of malarial parasite to drugs like chloroquine has prompted attempts to develo...........

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Widespread resistance of malarial parasite to drugs like chloroquine has prompted attempts to develop a malarial vaccine to combat malaria. Why is it difficult to develop an effective malaria vaccine?

Malaria is caused by several species of Plasmodium

Man does not develop immunity to malaria during natural infection

Vaccines can be developed only against bacteria

Man is only an intermediate host and not the definitive host

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Explanation:

Malaria is caused by several species of Plasmodium, so it is difficult to develop an effective malaria vaccine. Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type. Malaria causes symptoms that typically include fever, feeling tired, vomiting, and headaches. In severe cases it can cause yellow skin, seizures, coma, or death