With reference to Metabolomics Alteration, consider following statements

1. It is a very interesting approach to differentiate between the mild and severe cases of COVID-19 based on the determination of biomarkers from detailed metabolome or proteome investigations.
2. Metabolomics is the large-scale study of small molecules, commonly known as metabolites, within cells, biofluids, tissues or organisms.
3. It has been conducted by IIT-Bombay, in collaboration with hospitals in Mumbai on COVID-19 infected patients.

Select the correct statement.

Recently, the Science and Engineering Research Board (SERB) has decided to support exploration of metabolomics alteration in COVID-19 infected patients.

• The metabolic alteration of COVID-19 infected patients has been conducted by IIT-Bombay, in collaboration with hospitals in Mumbai.
• The exploration will identify potential biomarker candidates to predict progression from non-severe to severe COVID-19 conditions.

About Metabolomics

• It is the large-scale study of small molecules, commonly known as metabolites, within cells, biofluids, tissues or organisms.
• It is a powerful approach because metabolites and their concentrations, unlike other "omics" measures, directly reflect the underlying biochemical activity and state of cells / tissues. 

By: Shubham Tiwari