Explanation:

• Huntington disease (HD) is a progressive genetic disorder affecting the brain that causes uncontrolled movements, impaired coordination of balance and movement, a decline in cognitive abilities, difficulty in concentrating and memory lapses, mood swings and personality changes.
• It is caused by a mutation in a gene called HTT which are involved in the production of a protein called huntingtin.They provide the instruction for making the protein.
• When the genes mutate, they provide faulty instructions leading to production of abnormal huntingtin proteins and these form into clumps.
• There is currently no cure for Huntington’s disease and no way to slow or stop the brain changes it causes but drugs, physiotherapy and talk therapy can help manage some symptoms.