Explanation:

pyrethrum

Pyrethrum is a highly effective natural insecticide, which has been used for centuries against all manner of insect pests, obtained from by Tanacetum cinerariifolium. It is concentrated in the flower head. The active substance is six esters, known as pyrethrins, which work in combination to kill insects by targeting the nervous system of the insects. Therefore, commonly used as insect repellants.
Rotenone is a broad-spectrum insecticide which occurs naturally in the seeds and stems of several plants. It works by interfering with the electron transport chain in mitochondria therefore results in damaging DNA and other components of insects mitochondria.