Explanation:

- Muttiah Muralitharan: Sri Lankan legend, highest Test wicket-taker, but did not specialize in dismissing left-handers to this count.

- James Michael Anderson: England pace bowler, known for his skill against left-handers, but has not reached the 200 wicket mark against them first.

- Stuart Broad: Also an English pacer, prolific wicket-taker, but not the first to achieve this milestone against left-handers.

- Ravichandran Ashwin: Indian off-spinner, famous for troubling left-handed batters with his unique angles and drift, but is not the first ever to take 200 Test wickets against left-handers.

Correct Answer:

Option 2: James Michael Anderson