Read the following passage and answer the items that follow. Your answers to these items should be based on the passages only.

Although most of the Genetically Modified (GM) crops cultivated now are genetically engineered for a single trait, in future, crops genetically engineered for more than one trait will be the norm. Thus, biotechnology's role in agriculture and the regulation or the same cannot be understood solely in the context of the current generation of GM crops. Instead, there is a need to take a comprehensive look, taking into account various aspects, including socio-economic impacts, so that the potential or the technology can be harnessed while minimizing negative impacts. Given the importance of biotechnology in developing varieties that can help in climate change mitigation and adaptation, not using biotechnology as a part of the climate change action plan cannot be an option. Domestic regulation of biotechnology cannot be viewed in isolation of trade policy and obligations under various international treaties and conventions.

With reference to the above passage, the following assumptions have been made:

1. Biotechnology regulation is an evolving process.
2. Participation of people is needed in policy decisions regarding biotechnology regulation.
3. Biotechnology regulation should take into account socio-economic aspects in decision-making.
4. Wider involvement of political executive in biotechnology regulation improves its effectiveness in dealing with the country’s trade Policies and international obligations.

Which of the above assumptions are valid?