Consider the following statements regarding ‘Hydrogel developed for Targeted Breast Cancer Therapy’
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Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids.
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They serve as a stable reservoir for anti-cancer drugs, releasing it in a controlled manner while sparing healthy cells from harm.
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The hydrogel remained localised at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs.
Which of the statements given above is/are correct?
1&2 only
Incorrect Answer2&3 only
Incorrect AnswerExplanation:
Researchers from the Indian Institute of Technology-Guwahati (IIT-G) and the Bose Institute, Kolkata have developed an advanced injectable hydrogel for localised cancer treatment.
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Statement 1 is correct: Hydrogels are water-based, three-dimensional polymer networks capable of absorbing and retaining fluids. Their unique structure mimics living tissues, making them suitable for biomedical applications.
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The hydrogel, composed of ultra-short peptides — biocompatible and biodegradable building blocks of proteins — is designed to remain insoluble in biological fluids, ensuring it stays localised at the injection site.
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It responds to elevated glutathione (GSH) levels, a molecule abundant in tumour cells.
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Upon encountering high GSH levels, the hydrogel triggers a controlled drug release directly into the tumour, minimising its interaction with healthy tissues and reducing systemic side effects.
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Statement 2 is correct: They serve as a stable reservoir for anti-cancer drugs, releasing it in a controlled manner while sparing healthy cells from harm.
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Statement 3 is correct: The hydrogel remained localised at the tumour site, steadily releasing the drug over time without causing detectable side effects on other organs.
Hence option 4th is correct.
By: Shubham Tiwari ProfileResourcesReport error