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With reference to MicroRNA (MiRNA), consider the following statements
MiRNAs are single-stranded, binding target mRNA to prevent protein production by one of two distinct mechanisms.
mRNA is made from a DNA template during transcription.
Which of the statements given above is/are correct?
1 only
2 only
Both
None
Both the statements are correct.
MicroRNAs
MiRNAs are small, evolutionary conserved, single-stranded, non-coding RNA molecules that bind target mRNA to prevent protein production by one of two distinct mechanisms.
Mature miRNA is generated through two-step cleavage of primary miRNA (pri-miRNA), which is incorporated into the effector complex RNA-induced silencing complex (RISC).
The miRNA functions as a guide by base-pairing with the target mRNA to negatively regulate its expression.
The level of complementarity between the guide and mRNA target determines which silencing mechanism will be employed; cleavage of target messenger RNA (mRNA) with subsequent degradation or translation inhibition.
mRNA
Messenger RNA (mRNA) is a type of single-stranded RNA involved in protein synthesis.
mRNA is made from a DNA template during the process of transcription.
The role of mRNA is to carry protein information from the DNA in a cell’s nucleus to the cell’s cytoplasm (watery interior), where the protein-making machinery reads the mRNA sequence and translates each three-base codon into its corresponding amino acid in a growing protein chain.
So mRNA really is a form of nucleic acid that helps the human genome, which is coded in DNA, to be read by the cellular machinery.
Hence option 3rd is correct.
By: Shubham Tiwari ProfileResourcesReport error
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