Explanation:

In early stages of rheumatoid arthritis, the inflammation in the joints can cause tenderness and pain. There may not be as much redness or swelling as there is in later stages. Other early signs of rheumatoid arthritis may include joint stiffness that lasts at least 30 minutes, especially in the mornings. Some patients may have flare-ups, which can include fever, loss of appetite, and fatigue.