Explanation:

Only statements 1&2 are correct.

• Humans have 22 pairs of numbered chromosomes (autosomes) and one pair of sex chromosomes (XX or XY), for a total of 46.

• Each pair contains two chromosomes, one coming from each parent.

• Statement 3rd is incorrect: The X and Y chromosomes, also known as the sex chromosomes, determine the biological sex of an individual. (i.e. Sex Chromosomes: Determine biological sex (XX for females, XY for males)

Y chromosome

• The Y chromosome, often referred to as the “master of maleness”.

• Statement 2nd is correct: The Y chromosome of all living men is related through a single male ancestor who lived over 100,000 years ago.

• Statement 1st is correct: Y chromosome possesses genes linked to ageing and lifespan regulation.

• The Y chromosome carries the sex-determining region Y (SRY), which determines the development of male characteristics.

• Men experience a loss of the Y chromosome (LoY) with age, which is associated with higher frequencies of cancers, Alzheimer's disease, and a shorter lifespan.

• LoY in humans is associated with several debilitating medical conditions, including weak heart muscles, fibrosis, and heart failure.

Hence option 1st is correct.