Explanation:

Recently, the Indian Pharmacopoeia Commission (IPC) has issued a drug safety alert for doctors and patients about the use of painkiller mefenamic acid can lead to Drug Reactions with Eosinophilia and Systemic Symptoms (DRESS) Syndrome.

• It is a type of drug allergy that can occur as a reaction to a large variety of medications.

• It is sometimes referred to as DIHS (Drug Induced Hypersensitivity Syndrome).

• This syndrome causes a diverse array of clinical symptoms, anywhere from 2 to 8 weeks after initiating the offending drug. 

Symptoms

• Patients typically present with a rash, fever, and eosinophilia but can have a variety of symptoms including liver, lung, or kidney involvement.

• Also have a visceral involvement (hepatitis, pneumonitis, myocarditis, pericarditis, nephritis, and colitis) which is the major cause of morbidity and mortality in this syndrome.

Treatment

• The most important step to treat DRESS Syndrome is to stop the medication involved in the reaction, and sometimes, no further treatment is needed.

• It is largely supportive and symptomatic; corticosteroids are often used and sometimes immunosuppressants like cyclosporine.

Hence only statement 1st is correct.