Explanation:

Both statements are correct.

• Recombinant proteins are proteins engineered in the lab by inserting the gene coding for the protein into bacterial, viral, or mammalian cells.

• Typically, these proteins are produced in large bioreactors using the cells of a specific yeast which contains a unique promoter, called the alcohol oxidase (AOX) promoter. 

• The AOX promoter, activated by methanol, boosts recombinant protein production. This involves placing the desired gene near the AOX promoter, feeding yeast with glycerol or glucose, then adding methanol for protein activation.

• However, methanol poses risks like flammability, hazardousness, and production of harmful byproducts.

• An alternative, Monosodium Glutamate (MSG), activates a different yeast promoter, PEPCK, for safer protein production similar to methanol's process but without its risks. 

Hence option 3rd is correct.